You could look at http://warrior.archiveteam.org/ and https://github.com/ArchiveBox/good-karma-kit

I used to run a proxmox server with windows in a VM that had a GPU via gpu passthrough. Then connected to it via parsec. On my laptop connected to the local network it was pretty good.

The article actually says the desease is not the result of incest, but instead all people with the decease most likely share a common ancestor.