If the pig option included immune suppression drugs for the rest of your life, or for like 10 years until it wore out and you had to have another major surgery to replace it, mechanical valve plus blood thinners and a yearly blood draw sounds like the much better deal. I know blood thinners come with their own long term effects, but nothing compared to immune suppression.
Wormholes modeled with mainstream physics are incredibly unstable, to the point that they collapse before even a single particle is able to traverse them. Proposals for ways to stabilize a wormhole rely on models that have not yet been confirmed by experiment. So any answer you get is going to be little more than conjecture, and I don’t think you can get the scientific rigor it sounds like you’re looking for.